Verlag Hans Huber

International Journal for Vitamin and Nutrition Research, Nr. 2/2001:

Contents/Inhalt

Anne Linda van Kappel, Carmen Martínez-García, Solve Elmståhl,
Jean-Paul Steghens, Véronique Chajès, Franca Bianchini, Rudolf Kaaks and Elio Riboli
Plasma Carotenoids in Relation to Food Consumption in Granada (Southern Spain) and Malmö (Southern Sweden)
Zusammenfassung
Summary
Yoshiji Ohta, Takafumi Niwa and Takashi Yamasaki
Effect of Prolonged Marginal Ascorbic Acid Deficiency on Lenticular Levels of Antioxidants and Lipid Peroxide in Guinea Pigs
Zusammenfassung
Summary
Brahim Lachili, Henri Faure, Josiane Arnaud, Marie-Jeanne Richard, Cherifa Benlatreche, Alain Favier and Anne-Marie Roussel
Blood Micronutrients in Algeria, Relationships with Sex and Age
Zusammenfassung
Summary
Susan J. Fairweather-Tait, Gary M. Wortley, Birgit Teucher, Jack Dainty
Iron Absorption from a Breakfast Cereal: Effects of EDTA Compounds and
Ascorbic Acid
Zusammenfassung
Summary
Fereidoun Azizi, Sima Allahverdian, Parvin Mirmiran, Maziar Rahmani, Fatemeh Mohammadi
Dietary Factors and Body Mass Index in a Group of Iranian Adolescents: Tehran Lipid and Glucose Study-2
Zusammenfassung
Summary
Marta González, Belén Caride, Asunción Lamas and Cristina Taboada
Dietary Effects of Marine Food Intake on Intestinal and Hepatic Enzyme Activities in Rats
Zusammenfassung
Summary



Zusammenfassungen / Summaries



Contents/
Inhalt
   

Plasma Carotenoids in Relation to Food Consumption in Granada (Southern Spain) and Malmö (Southern Sweden)

Anne Linda van Kappel1, Carmen Martínez-García2, Solve Elmståhl3,
Jean-Paul Steghens4, Véronique Chajès1, Franca Bianchini1, Rudolf Kaaks1 and Elio Riboli1

1 Unit of Nutrition and Cancer, International Agency for Research on Cancer, 150 cours Albert-Thomas, 69372 Lyon Cédex 08, France
2 Granada Cancer Registry, Escuela Andaluza de Salud Publica, E-18080 Granada, Spain
3 Department of Community Medicine, Lund University, Malmö University Hospital, S-20502 Malmö, Sweden
4 Laboratoire de Biochimie C, Hôpital Edouard Herriot, 69437 Lyon Cédex 03, France

(Summary)

Summary

We conducted a cross-sectional pilot study on healthy pre-menopausal women (aged 45­50 years) living in Granada, in the south of Spain (n = 39) and Malmö, in the south of Sweden (n = 38) in order to compare their plasma carotenoid levels and to investigate the relationship between the differences in food consumption. Plasma concentrations of six carotenoids were measured using high performance liquid chromatography, habitual diet (at individual level) was estimated by food frequency questionnaires and 24-hour diet recalls were used for standardised measurement of diet at group-level.
We found that women in Granada consumed more fruit and vegetables than women in Malmö. Plasma concentrations of beta-cryptoxanthin, lycopene, zeaxanthin, total carotenoids and alpha-tocopherol were higher in Granada than in Malmö, although plasma concentrations of alpha-carotene and retinol were higher in Malmö. Both within and between study centres, consumption of fruit and vegetables correlated positively with plasma concentrations of different carotenoids.
The study showed that differences in consumption of fruit and vegetables between the two European centres were reflected in plasma carotenoid concentrations.

Key words

Carotenoids, plasma, diet, Spain, Sweden

International Journal for Vitamin and Nutrition Research,
Band 71, 2001, Heft 2, © Verlag Hans Huber AG, Bern


Contents/
Inhalt
   

Effect of Prolonged Marginal Ascorbic Acid Deficiency on Lenticular Levels of Antioxidants and Lipid Peroxide in Guinea Pigs

Yoshiji Ohta1, Takafumi Niwa2 and Takashi Yamasaki3

1 Department of Chemistry, School of Medicine, Fujita Health University, Toyoake, Aichi 470-1192, Japan
2 Department of Ophthalmology, School of Medicine, Fujita Health University, Toyoake, Aichi 470-1192, Japan
3 Department of Ophthalmology, Nakatsugawa City Hospital, Nakatsugawa, Gifu 508-0011, Japan

(Summary)

Summary

We examined the effect of prolonged marginal ascorbic acid deficiency of the levels of antioxidants and lipid peroxide in lenses of guinea pigs in order to clarify lenticular antioxidant status under ascorbic acid deficiency. Male guinea pigs aged 4 weeks were given a scorbutic diet (20 g/animal per day) with either marginally deficient ascorbic acid (0.5 mg/animal per day) or sufficient ascorbic acid (1 g/animal per day) in drinking water for 3 and 6 months. The deficient group showed no lens opacity during the administration period. The deficient group had 62.3 and 53.9% of lenticular ascorbic acid content in the sufficient group at 3 and 6 months of ascorbic acid deficiency, respectively. There were no differences in lenticular contents of reduced glutathione and thiobarbituric acid reactive substances, an index of lipid peroxidation, between both groups at 3 and 6 months of ascorbic acid deficiency, while the deficient group tended to have higher lenticular vitamin E content than the sufficient group. The deficient group had higher serum vitamin E concentration than the sufficient group at 3 and 6 months of ascorbic acid deficiency. These results indicate that lenticular antioxidant status is maintained well in guinea pigs with prolonged marginal ascorbic acid deficiency, which may result in no cataract formation.

Key words

Ascorbic acid, reduced glutathione, vitamin E, lipid peroxide, antioxidant status, marginal ascorbic acid deficiency (guinea pig), lens

International Journal for Vitamin and Nutrition Research,
Band 71, 2001, Heft 2, © Verlag Hans Huber AG, Bern


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Are the Serum 25-Hydroxyvitamin D Concentrations in Winter Associated with Forearm Bone Mineral Density in Healthy Elderly Japanese Women?

Brahim Lachili1, Henri Faure2, Josiane Arnaud2, Marie-Jeanne Richard2, Cherifa Benlatreche3, Alain Favier2 and Anne-Marie Roussel2

1 Laboratoire Central de Biochimie, CHU Benflis Touhami, Boulevard Mohamed Boudiaf, 05000 Batna, Algeria
2 LBSO, Laboratoire de Biochimie, UFR de Médecine-Pharmacie, Avenue des maquis du Grésivaudan, 38700 La Tronche, France
3 Unité de Recherche, Faculté de Médecine, Chalet des pins, BP 125, 25000 Constantine, Algeria

(Summary)

Summary

Despite trace elements and vitamins are major public health problems in some African countries, there are few studies reporting micronutrient status in North Africa. Therefore, it could be interesting to evaluate plasma concentrations of vitamin A, E and b-carotene, along with zinc, copper, selenium erythrocyte glutathione peroxidase and superoxide dismutase in Algeria.
Volunteers were randomly recruited in Constantine, Batna and Mila. Vitamins, trace elements and enzymes were measured in the University Hospital of Grenoble.
455 persons were included in the study. Subjects were divided in 3 groups: group I: 15 girls and 12 boys who were 6 to 12.9 years old, group II: 190 women and 192 men 13 to 49.9 years old, group III: 24 women and 24 men 50 to 65 years old.
Plasma concentrations of micronutrients and enzymes are close to those commonly observed in Europe, except for vitamin A concentrations. Indeed, retinol levels are 30­35% lower than those reported in European countries, moreover almost 8% of the population showed retinol concentrations less than 1.05 mmol/l. b-Carotene levels were also lower than in the French average population. Ten per cent of the population had plasma zinc levels lower than 10.6 mmol/l.
Vitamin E, copper and selenium status seems satisfactory in Algeria. Vitamin A is not a public health problem, however a significant percentage of residents exhibits impaired vitamin A levels and may benefit from retinol supplementation. Larger studies are needed, and particularly in children, to detect possible higher prevalence of vitamin A deficiency in poor socio-economical classes and in inner geographic areas.

Key words

Vitamin A, vitamin E, carotene, zinc, copper, selenium, Algeria, glutathione peroxidase, superoxide dismutase

International Journal for Vitamin and Nutrition Research,
Band 71, 2001, Heft 2, © Verlag Hans Huber AG, Bern


Contents/
Inhalt
   

Iron Absorption from a Breakfast Cereal: Effects of EDTA Compounds and Ascorbic Acid

Susan J. Fairweather-Tait, Gary M. Wortley, Birgit Teucher, Jack Dainty

Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, Norfolk, UK

(Summary)

Summary

Sodium iron ethylenediaminetetracetic acid (NaFeEDTA) has been recommended for food fortification programmes to improve iron status but its performance in commercial products has not been evaluated. The effect of EDTA on iron absorption from fortified cornflakes, given as part of a typical Western breakfast, was determined in a double-blind randomised study with 20 non-anaemic female volunteers, using experimentally prepared iron compounds, enriched with 58Fe, and faecal monitoring. Five meals were compared: hydrogen reduced iron, hydrogen reduced iron plus Na2EDTA (molar ratio EDTA:Fe 1:2), hydrogen reduced iron plus NaFe(III)EDTA at two different molar ratios (EDTA:total Fe 1:3 and 1:2), and hydrogen reduced iron plus 15 mg ascorbic acid (ascorbic acid:Fe 1.3:1). The iron and EDTA compounds were accurately weighed into gelatine capsules and taken with unfortified cornflakes, semi-skimmed milk and tea on two consecutive days; the iron dose per meal was 3.75 mg. Iron absorption from all five test meals was measured in each volunteer with a minimum wash-out period of 2 weeks between tests. Geometric mean iron absorption (%) from the 5 tests was 14.1, 17.6, 20.6, 24.4 and 17.5 respectively (equivalent to 0.5­0.9 mg absorbed iron). There was a significantly higher iron absorption from the mixture of reduced iron and NaFe(III)EDTA (EDTA:Fe 1:2) than from reduced iron alone (p = 0.014). It is not known whether the higher absorption was from reduced iron or NaFeEDTA or both. Absorption was not increased significantly with NaFe(III)EDTA (EDTA:Fe 1:3), Na2EDTA (EDTA:Fe 1:2) or ascorbic acid (15 mg).

Key words

Iron absorption, bioavailability, EDTA, stable isotopes, breakfast cereals

International Journal for Vitamin and Nutrition Research,
Band 71, 2001, Heft 2, © Verlag Hans Huber AG, Bern


Contents/
Inhalt
   

Dietary Factors and Body Mass Index in a Group of Iranian Adolescents: Tehran Lipid and Glucose Study-2

Fereidoun Azizi, Sima Allahverdian, Parvin Mirmiran, Maziar Rahmani, Fatemeh Mohammadi

Endocrine Research Centre, Shaheed Beheshti University of Medical Sciences, Tehran, I.R. Iran

(Summary)

Summary

Objective: To study the prevalence of overweight and obesity in an adolescent population in Tehran and to determine possible association with energy and nutrient intake and distribution of energy over the day.
Method: A cross-sectional study on 177 boys and 244 girls between 10­19 years old was performed. Overweight and obesity were defined by using recommended body mass index (BMI) cut-off values for adolescents. Total energy intake, percent of energy derived from protein, carbohydrate and fat and percent of energy supplied by each meal and snack were assessed by means of two 24-hour dietary recalls.
Results: Prevalence of overweight and obesity was 10.7 and 5.1 in boys and 18.4 and 2.8 in girls, respectively. The composition of diet was not different between overweight/obese and normal weight subjects. BMI was related with breakfast energy percentage in girls (r = ­0.18, p < 0.01), with total energy intake in boys (r = 0.23, p < 0.01), and with lunch energy percentage in both sexes. In boys (r = 0.16, p < 0.05) and in girls (r= 0.22, p < 0.01).
Conclusion: High prevalence of overweight and obesity among adolescents was seen. In boys some relationship between total energy intake, distribution of energy over the day and BMI was seen. In girls BMI was only related with distribution of energy over the day.

Key words

Obesity, adolescents, dietary survey, energy intake, breakfast

International Journal for Vitamin and Nutrition Research,
Band 71, 2001, Heft 2, © Verlag Hans Huber AG, Bern


Contents/
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Supplementation with Vitamin E and/or Zinc does not Attenuate Atherosclerosis in Apolipoprotein E-deficient Mice fed a High-Fat, High-Cholesterol Diet

Marta González, Belén Caride, Asunción Lamas and Cristina Taboada

Department of Physiology, Faculty of Pharmacy, University of Santiago de Compostela, 15706, Spain

(Summary)

Summary

Dietary effects of two diets high in protein from two marine species (Haliotis tuberculata and Anemonia viridis) as compared to a high-quality patron protein such as casein (or casein supplemented with olive oil) on intestinal and hepatic enzymes were studied.
After 23 days, the two marine species as diet compared to casein increased the disaccharidase and alkaline phosphatase activities. Feeding Haliotis tuberculata meal produced a decrease on intestinal leucine aminopeptidase activity. The hepatic gamma-glutamyltranspeptidase activity decreased slightly in animals fed Haliotis tuberculata meal. Supplementation of casein with olive oil tended to decrease the intestinal and hepatic enzyme activity.

Key words

Protein, amino acid, casein, Anemonia viridis, Haliotis tuberculata, disaccharidases, alkaline phosphatase, leucine aminopeptidase, gamma-glutamyltranspeptidase

International Journal for Vitamin and Nutrition Research,
Band 71, 2001, Heft 2, © Verlag Hans Huber AG, Bern


wwwadmin@HansHuber.com, 28. März 2001